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[目的]观察银杏达莫注射液联合低分子肝素治疗不稳定型心绞痛的疗效。[方法]将住院的107例不稳定型心绞痛患者随机分为治疗组54例和对照组53例。治疗组在常规治疗的基础上加用银杏达莫注射液20ml+生理盐水250ml静滴,1次/d;同时给予低分子肝素4100Iu皮下注射,每12h/次,连续用7d,对照组采用常规的抗心绞痛药物治疗,药物包括硝酸酯类口服,美托洛尔口服,肠溶阿司匹林口服等。观察两组患者心绞痛症状和心电图改善情况与血液流变学指标变化,及对患者血、尿常规与肝肾功能的影响。[结果]治疗组心绞痛症状、心电图改善情况及血液流变学指标较对照组均明显改善,而两组患者的血、尿常规与肝肾功能无改变。[结论]银杏达莫注射液联合低分子肝素对不稳定型心绞痛的治疗效果显著,且无毒副作用,值得推广。
[Objective] To observe the curative effect of Yinxingdamo injection combined with low molecular weight heparin in the treatment of unstable angina pectoris. [Methods] 107 patients with unstable angina pectoris were randomly divided into treatment group (54 cases) and control group (53 cases). The treatment group on the basis of conventional treatment plus ginkgo dipyridamole injection 20ml + 250ml saline infusion, 1 / d; given low molecular weight heparin 4100Iu subcutaneous injection, every 12h / times for 7d, the control group using conventional Anti-angina drug treatment, drugs including oral nitrates, metoprolol oral, enteric-coated aspirin and so on. The changes of angina pectoris and electrocardiogram (ECG) and hemorheology indexes in two groups were observed, and the effects of blood, urine and liver and kidney function were observed. [Results] The improvement of angina pectoris, electrocardiogram and hemorheology in the treatment group were all better than those in the control group. The blood, urine and liver and kidney function of the two groups were not changed. [Conclusion] The combination of Ginkgo-Damo injection and low-molecular-weight heparin has a significant effect on the treatment of unstable angina pectoris and has no toxicity and side effects and is worthy of promotion.