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目的探讨癫痫与白细胞介素－６（ＩＬ－６）的关系。方法采用双抗体夹心ＥＬＩＳＡ法对３３例正常对照和３６例癫痫患者血清ＩＬ－６水平进行检测。结果癫痫组血清ＩＬ－６水平显著高于对照组，血清ＩＬ－６水平变化与癫痫患者的性别、年龄、病程及发作类型无关，但与发作频率及距末次发作时间密切相关，抗癫痫药物对血清ＩＬ－６水平无明显影响。结论ＩＬ－６与癫痫发病密切相关
Objective To investigate the relationship between epilepsy and interleukin-6 (IL-6). Methods Serum IL-6 levels in 33 normal controls and 36 patients with epilepsy were measured by double antibody sandwich ELISA. Results The level of serum IL-6 in epilepsy group was significantly higher than that in control group. The change of serum IL-6 level was not related to the gender, age, course of disease and type of epilepsy. However, the frequency of seizure and the frequency of last episode were significantly correlated with antiepileptic drugs Serum IL-6 levels had no significant effect. Conclusion IL-6 and epilepsy are closely related