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作者为了验证载脂蛋白以E(apo E)e4等位基因与脑淀粉样血管病(CAA)出血的关系及首次出血年龄的关系,作了如下研究。 选择45例脑叶出血病人(男22例,女23例),排除年龄<50岁或其他原因引起的出血者,应用梯度-回波MRI扫描技术,根据出血的数目和部位将病人分为3类:1.病理(尸检或活检)证实为CAA或局限于皮质/皮质下多发出血者为肯定/可能CAA出血,共27例;2.单一脑叶出血者为可疑CAA出血,共12例;3.脑叶出血合并深部出血者为混合性出血,共6例;同时与18
In order to verify the relationship between the apolipoprotein E (apo E) e4 allele and cerebral hemorrhage in cerebral amyloid angiopathy (CAA) and the relationship between the first bleeding age, the authors studied the following. 45 patients with cerebral lobar hemorrhage (22 males and 23 females) were selected to exclude those who were under 50 years of age or other causes of bleeding. Gradient-echo MRI was used to divide the patients into 3 Classes: 1. Pathology (autopsy or biopsy) confirmed as CAA or localized in the cortex / subcortical bleeding were positive / probable CAA hemorrhage, a total of 27 cases; 2. Single lobar hemorrhage was suspected CAA bleeding, a total of 12 cases; 3. Cerebral lobe hemorrhage combined with deep bleeding were mixed bleeding, a total of 6 cases; at the same time with 18