论文部分内容阅读
肝细胞广泛坏死是重型病毒性肝炎的基本病理特征。目前认为由细胞毒性Ｔ淋巴细胞 (Ｃｙｔｏｔｏｘｉｃ ｉｔｙＬｙｍｐｈｏｃｙｔｅ ,ＣＴＬ)介导的细胞毒作用是导致肝细胞坏死的主要免疫机理 ,在此基础上继发的肠源性内毒素血症 ,激活肝内外单核巨噬细胞释放以肿瘤坏死因子α(
Extensive necrosis of hepatocytes is a fundamental pathological feature of severe viral hepatitis. At present it is thought that the cytotoxic effect mediated by Cytotoxicity Lymphocyte (CTL) is the main immune mechanism leading to hepatocyte necrosis. Based on this, secondary enterogenous endotoxemia is activated, Macrophages release to tumor necrosis factor alpha (