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目的为了研究粉尘作业工人的免疫球蛋白和超氧化物歧化酶（ＳＯＤ）的改变情况，探讨尘肺早期诊断的辅助指标。方法对男性的粉尘作业工人（１０１人）、非接尘工人（２９人）和尘肺患者（２０人）血清中免疫球蛋白（ＩｇＧ、ＩｇＡ、ＩｇＭ）及ＳＯＤ的含量检测。结果发现粉尘作业工人及尘肺患者血清中ＩｇＧ含量升高的个体比例高于非接尘工人，而接尘工人及尘肺患者血清中的ＳＯＤ含量明显低于非接尘工人，而尘肺患者又明显低于接尘工人。结论从上述观察指标的结果发现，接上与不接生的工人有显著性差异。为此，我们建议把血清中ＩｇＧ、ＳＯＤ含量作为尘肺早期诊断的参考指标。
Objective To study the changes of immunoglobulin and superoxide dismutase (SOD) in dusty workers and to explore the auxiliary indicators of early diagnosis of pneumoconiosis. Methods Serum immunoglobulin (IgG, IgA, IgM) and SOD in male workers (101 people), non-exposed workers (29 people) and pneumoconiosis patients (20 people) were measured. The results showed that the proportion of serum IgG in dust-exposed workers and pneumoconiosis patients was higher than that in non-dust-exposed workers, while SOD levels in sera of dust-exposed workers and pneumoconiosis patients were significantly lower than those in non-dust-exposed workers and significantly lower in pneumoconiosis patients In the dust workers. Conclusions From the above observations, we found that there was a significant difference between workers on and without delivery. To this end, we suggest that the serum IgG, SOD content as a reference for the early diagnosis of pneumoconiosis.