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目的 ：观察胸部放射治疗时的肺功能损害，探讨肺功能预测放疗损伤的临床意义。方法：３６ 例肺部肿瘤患者在放疗前１ 周与放疗后１ 月内测定 Ｖ Ｃ、 Ｍ Ｂ Ｃ、 Ｆ Ｖ Ｃ、 Ｆ Ｅ Ｖ１ 、 Ｒ Ｖ／ Ｔ Ｌ Ｃ、 Ｂ Ｒ 及 Ｂ Ｒ％ 、 Ｄｌ Ｃ Ｏ等肺功能指标。结果： 放疗后 Ｄｌ Ｃ Ｏ 降低最为显著（１１４ ．６８ ±２３ ．１１ ，１１１ ．６９ ±２７ ．４０ ， Ｐ＜ ０ ．０１） ， Ｆ Ｖ Ｃ 下降，差异有显著性（９３ ．７９ ±１９６５ ，７４ ．４４ ±１９ ．２１ ， Ｐ＜ ０ ．０５） ， Ｆ Ｅ Ｖ１ 有所升高，其他指标改变不明显。结论：放疗后１ 月内肺功能损害以弥散功能损害为主， Ｄ Ｌ Ｃ Ｏ 明显降低，可作为一项预测指标。
Objective: To observe the lung function impairment during chest radiotherapy and explore the clinical significance of lung function prediction radiotherapy injury. METHODS: V C, M B C, F V C, F E V1, R V / T L C, B R and B R%, Dl were determined in 36 patients with lung cancer 1 week before radiotherapy and 1 month after radiotherapy. C O and other lung function indicators. Results: The Dl C O decreased most significantly after radiotherapy (114.68±23.11, 111.69±27.40, P<0.01), and the FVC decreased, the difference was significant (93.79 ±1965). 74.44 ± 19.21, P < 0. 05), F E V1 increased, other indicators did not change significantly. CONCLUSIONS: In the first month after radiotherapy, the impairment of lung function was dominated by diffuse functional impairment, and the D L C O was significantly decreased, which can be used as a predictor.