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近来药物引起风湿样综合征现象已日益增多,本文介绍药物引起风湿样综合征的范围及检测时各综合征表现的变异性。供医药人员参考。 一、药物性关节病和自身免疫病 1.药物性红斑狼疮(DILE)它与系统红斑狼疮(SLE)不同,发生于用药期间,停药后临床特征消失,无SLE临床预兆或实验室特征。与DILE相关的药物已达50种以上,除口服避孕药外,多种抗生素、含硫药物、西米替丁、光敏药物(补骨脂)均可促使SLE恶化。Cush(1985年)、Alballa(1987年)先后
Recent drug-induced rheumatoid syndrome has been increasing, this article describes the scope of the drug-induced rheumatoid arthritis syndrome and the performance of the test variability. For medical staff reference. First, drug-induced joint disease and autoimmune diseases 1. Drugs lupus erythematosus (DILE) It is different from systemic lupus erythematosus (SLE), occurred during the medication, the clinical features disappeared after stopping, no SLE clinical signs or laboratory features. DILE-related drugs have reached more than 50, in addition to oral contraceptives, a variety of antibiotics, sulfur drugs, cimetidine, photosensitive drugs (psoralen) can promote deterioration of SLE. Cush (1985), Alballa (1987) successively