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目的 观察比较异丙酚联合芬太尼佳苏仑和异丙酚复合芬太尼用于老年人无痛肠镜检查时对呼吸循环的抑制程度,以寻求更安全有效的方法。方法 随机双盲抽取无痛肠镜检查的老年患者 60 例,分为异丙酚-芬太尼组(Ⅰ组)和异丙酚-芬太尼-佳苏仑组(Ⅱ组),每组30例,Ⅰ组麻醉时缓慢静注异丙酚、芬太尼,Ⅱ组加用佳苏仑。观察两组的麻醉效果及对呼吸循环的抑制程度。结果 两组的麻醉效果无明显差异(P>0 05),但Ⅱ组对呼吸的抑制程度明显低于Ⅰ组(P<0 01)。结论 佳苏仑能有效对抗异丙酚、芬太尼的呼吸抑制作用,提高老年患者无痛肠镜检查的安全性,同时不影响麻醉效果。
Objective To compare the inhibitory effect of propofol combined with Isuenolsufen and Propofol and fentanyl on respiratory circulation during painless colonoscopy in the elderly in order to find a safer and more effective method. Methods Sixty elderly patients with painless colonoscopy were randomly divided into three groups: propofol-fentanyl (group Ⅰ) and propofol-fentanyl-sulphones (group Ⅱ), and each group Thirty patients in group Ⅰ were anesthetized with propofol and fentanyl slowly, while those in group Ⅱ were given good sunsulen. The anesthetic effects and the degree of inhibition of respiratory cycle were observed in both groups. Results There was no significant difference in anesthetic effect between the two groups (P> 0.05), but the inhibition of respiration in group Ⅱ was significantly lower than that in group Ⅰ (P <0.01). Conclusion Allsullen can effectively resist the respiratory inhibition of propofol and fentanyl and improve the safety of painless colonoscopy in elderly patients without affecting the anesthetic effect.