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目的探讨D-二聚体(DD)与血清同型半胱氨酸(Hcy)测定在2型糖尿病中的临床意义。方法应用DD与HCy测定2型糖尿病患者75例,健康对照组36例。DD测定采用免疫比浊法,Hcy测定采用循环酶法,并进行统计学处理。结果2型糖尿病患者DD为386±98ng/L,Hcy为18.13±2.32μmol/L。对照组DD为168±58ng/L,HCy为9.88±3.47μmol/L。两组DD与HCy结果比较均有非常显著性差异(P<0.01)。结论DD与HCy测定对2型糖尿病的诊断、观察病情发展具有较好的应用价值。
Objective To investigate the clinical significance of D-dimer (DD) and serum homocysteine (Hcy) in type 2 diabetes. Methods 75 cases of type 2 diabetes mellitus and 36 cases of healthy control group were measured by DD and HCy. DD assay using immunoturbidimetry, Hcy determination by circulating enzyme method, and statistical analysis. Results DD patients with type 2 diabetes were 386 ± 98 ng / L and Hcy was 18.13 ± 2.32 μmol / L. The control group DD 168 ± 58ng / L, HCy 9.88 ± 3.47μmol / L. The DD and HCy results between the two groups were significantly different (P <0.01). Conclusion DD and HCy have good value in diagnosis of type 2 diabetes mellitus and observation of disease development.