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目的:探讨低钠血症与慢性重症肝炎病情发展及预后的关系。方法:根据低钠血症判定标准将128例慢重肝分为轻度、中度、重度低钠血症及血钠正常组,结合预后等分析其间关系。结果:本组低钠血症发生率为57.0％,伴有低钠血症的慢重肝均有肝性脑病、肝肾综合症、自发性腹膜炎等并发症。慢重肝中、晚期多伴有低钠血症,未愈率与低钠血症程度成正比,难以纠正的低钠血症预后更差(未愈率93.1％)。结论:慢重肝病情发展及预后与低钠血症有明显相关性。慢重肝中、晚期或/和并发症多者更易发生低钠血症。临床上在慢重肝的治疗中应积极纠正低钠血症以提高存活率。
Objective: To investigate the relationship between hyponatremia and progression of disease and prognosis in patients with chronic severe hepatitis. Methods: According to the criterion of hyponatremia, 128 patients with chronic severe liver were divided into mild, moderate and severe hyponatremia and normal sodium group, and the relationship was analyzed according to the prognosis. Results: The incidence of hyponatremia in this group was 57.0%. All the patients with hyponatremia had hepatic encephalopathy, hepatorenal syndrome and spontaneous peritonitis. Slowly severe liver, late with more associated with hyponatremia, unhealed rate is proportional to the degree of hyponatremia, difficult to correct the prognosis of hyponatremia worse (unhealed up 93.1%). Conclusion: The development of severe chronic liver disease and its prognosis have obvious correlation with hyponatremia. Slowly severe liver, advanced and / or more complications are more prone to hyponatremia. Clinically in the treatment of chronic severe liver hyponatremia should be actively corrected to improve the survival rate.