In vivo exploration of the functional activity of the non-coding 8q24 prostate cancer risk locus

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Genome-wide association studies (GWAS) have successfully identified a substantial number of risk variants for prostate cancer [1-10]. In total, more than 20 single nucleotide polymorphisms (SNPs) that predispose to prostate malignancy have been found scat-tered throughout the genome in coding and non-coding regions.
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