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目的 分析广东省江门市13例寨卡病毒感染者生物样品病毒核酸结果.方法 采用描述性方法对2016年2-4月江门市报告的寨卡病毒感染者进行流行病学分析.采用荧光定量逆转录聚合酶链反应(qRT-PCR)方法检测研究对象的血液、尿液和唾液寨卡病毒核酸.结果 2016年2-4月江门市共确诊10例寨卡病毒病病例和发现3例寨卡病毒隐性感染者,均自委内瑞拉输入.13例感染者中,男性6例,女性7例;最小年龄5岁,最大年龄46岁,中位数是19岁,≤14岁儿童占46.15％ (6/13).寨卡病毒核酸阳性检出持续时间,血液最短0 d,最长4d,中位数0d;尿液最短2d,最长32 d,中位数5.5d;唾液最短Od,最长10 d,中位数3.5d;尿液样品比血液样品病毒核酸阳性持续时间长(P＜0.01);唾液样品比血液样品病毒核酸阳性持续时间长(P＜0.05).结论 寨卡病毒感染者血液、尿液和唾液3种生物样品病毒核酸阳性持续时间不一致.“,”Objective To analyze the results of Zika virus nucleic acid detection of biological samples from 13 Chinese returning to Jiangmen city after viral infection in a foreign country.Methods Medical records were extracted and blood,urine and saliva samples were collected for all Zika virus infected patients reported in Jiangrnen city of Guangdong province between February and April 2016.All collected samples were detected for Zika virus nucleic acid with fluorescent quantitative real time reverse transcription-polymerase chain reaction (qRT-PCR).Results Totally 10 overt and 3 covert Zika virus infections were reported in Jiangmen city during the 3-month period and all the reported cases were Chinese returning to China from Venezuela.Of the 13 cases,6 were male and 7 were female;the minimum age of the cases was 5 years and the maximum was 46 years,with a median age of 19 years;46.15％ (6) of the cases were children under 14 years old.The positive duration of Zika virus nucleic acid detection ranged 0-4 days for blood,2-32 days for urine,and 0-4 days for saliva samples,with the medians of 0,5.5,3.5 days,respectively;both the positive duration of urine and saliva samples were significantly longer than that of blood (P ＜ 0.01 and P ＜ 0.05).Conclusion The positive duration of viral nucleic acid is different for blood,urine,and saliva samples from Zika virus infected people.