神经病理性疼痛的机制尚未阐明,传统观点认为CNS内调节疼痛信号传导的主要是脊髓背角和脑干,间脑和大脑皮层被认为是与疼痛体验(辨别、情感和情绪)或与疼痛相关运动有关。最近脑成像技术(如功能性磁共振成像fMRI)和新的示踪技术发展使得对脊髓以上中枢神经系统在疼痛控制中的作 The mechanism of neuropathic pain has not yet been elucidated. Traditionally, it has been proposed that the dorsal horn of the spinal cord and brainstem, which mediate pain signaling in the CNS, are thought to be associated with pain experiences (discrimination, emotion and mood) or with pain-related movements related. Recent advances in brain imaging technologies such as fMRI (functional magnetic resonance imaging) and the development of new tracing techniques have made it possible for the central nervous system above the spinal cord in pain management