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Concentrations of serum calcium, phosphorus, sodium, chlorine and potassium of growing yak born from a nuclear breeding herd in 1995,1996 and 1997(classified as groups G3, G2 and G1) were determined bimonthly from September 1997 to July 1998. The result showed that the concentrations of serum macro-minerals demonstrated a month/season pattern and both calcium and phosphorus reached the highest in September(11.36mg/dl and 6.82 mg/dl, respectively). The animals in G1 had a very high serum phosphorus concentration due to their young age and incomplete weaning in the early times of sampling. The ratio of calcium to phosphorus was generally higher than that recommended for cattle and demonstrated a great variation in month/season. The results indicated that the deficiencies of phosphorus, sodium and probably calcium were common in the pasture on the Qinghai-Tibetan Plateau.