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目的:探讨身体质量指数(BMI)、腰臀围比(WHR)与胆道癌的关系。方法:采用非条件logistic回归模型分析身体质量指数、腰臀围比与胆道癌的关系。结果:与正常BMI组比较,胆囊癌女性20～29岁、30～39岁肥胖组的OR与趋势检验均达到或接近显著水平。与腰臀围比四分位最低组比较,胆囊癌和肝外胆管癌男女性最高四分位组OR和趋势检验均达到显著水平。结论:青年时期肥胖可能会增加胆囊癌的发病风险;腰臀围比也是胆囊癌和肝外胆管癌独立的危险因素。
Objective: To investigate the relationship between body mass index (BMI), waist-hip ratio (WHR) and biliary tract cancer. Methods: Non-conditional logistic regression model was used to analyze the relationship between body mass index, waist-hip ratio and biliary tract cancer. Results: Compared with the normal BMI group, the odds ratio (OR) and trend of 20- to 29-year-old and 30-39-year-old obese women in Gallbladder cancer all reached or approached a significant level. Compared with the lowest quartile of waist and hip circumference, the OR and trend test of the highest quartile of gallbladder and extrahepatic cholangiocarcinoma both reached significant level. Conclusion: Obesity in youth may increase the risk of gallbladder cancer; waist-hip ratio is also an independent risk factor for gallbladder cancer and extrahepatic cholangiocarcinoma.