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目的 探讨我国肺癌高发区之一陕西宝鸡市肺癌的危险因素。方法 采用病例 -对照研究。病例为宝鸡市 1 992～ 1 996年恶性肿瘤监测点登记的全部肺癌病人共 63例 ,按 1∶ 3比例配对选取 1 89例健康人为对照。共调查十类危险因素、78个问题。结果 单因素分析结果达到显著性水平的危险因素有吸烟、室内微环境污染、家庭经济状况、男性致癌物接触史 ;多因素分析结果基本一致。其中做饭取暖燃料种类 (液化气、蜂窝煤、烟煤 )、排气扇使用情况 (经常用、偶尔用、不用 ) ,年均收入存在明显趋势性 (趋势χ2检验 P <0 .0 5)。结论 除吸烟等其它因素外 ,宝鸡市肺癌与当地燃料种类及使用方式存在联系。
Objective To explore the risk factors of lung cancer in Baoji City, Shaanxi, a high-risk area of lung cancer in China. Methods Case-control studies were used. A total of 63 cases of lung cancer patients registered at the malignant tumor monitoring sites in Baoji from 1 992 to 1 996 were selected, and 1, 89 healthy persons were selected as controls in a ratio of 1:3. A total of 10 types of risk factors and 78 problems were investigated. RESULTS: The risk factors for single factor analysis to reach significant levels were smoking, indoor micro-environmental pollution, family economic status, and male exposure to carcinogens. Multivariate analysis was basically consistent. Among the cooking fuel types (liquefied gas, briquette, bituminous coal) and exhaust fan usage (usually, occasionally, and unused), there is a clear trend in the average annual income (trend χ2 test P<0.05). Conclusions In addition to smoking and other factors, there is a link between lung cancer and local fuel types and usage patterns in Baoji City.