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目的:探讨内镜下碘染色对早期食管癌及癌前病变的筛查价值。方法:采用内镜下碘染色筛查40～69岁的人群中无症状志愿体检者1114例,并针对其中所筛检出的早期食管癌、食管异型增生者,比较其内镜筛查时于碘液染色前后的内镜下阳性率;以及比较早期食管癌、食管异型增生者于碘液染色前后的检出率。结果:本研究所检出的早期食管癌、食管异型增生者53例中,内镜筛查时于碘液染色后的内镜下阳性率(100%)明显高于碘液染色前的内镜下阳性率(30.2%)(P<0.001);本研究中于碘液染色后食管癌、食管异型增生者检出率(4.76%)明显高于碘液染色前食管癌、食管异型增生者检出率(1.44%)(P<0.001)。结论:内镜下碘染色能显著提高食管粘膜内镜下阳性率、显著提高早期食管癌及癌前病变检出率,值得临床推广应用。
Objective: To investigate the screening value of endoscopic iodine staining for early esophageal cancer and precancerous lesions. Methods: 1114 cases of asymptomatic volunteers were screened by iodine staining in endometrial in 40-69 years old group, and compared with those of early stage esophageal cancer and esophageal dysplasia, Iodine staining before and after the endoscopic positive rate; and more early esophageal cancer, esophageal dysplasia in iodine staining before and after the detection rate. Results: The positive rate (100%) in endoscopic diagnosis of early esophageal cancer and esophageal dysplasia detected by iodine staining was significantly higher than that before iodine staining (30.2%) (P <0.001). In this study, the detection rate of esophageal cancer and esophageal dysplasia (4.76%) in iodine staining was significantly higher than that of iodine staining before esophageal cancer and esophageal dysplasia Out rate (1.44%) (P <0.001). Conclusion: Endoscopic iodine staining can significantly improve the positive rate of endoscopic esophageal mucosa, significantly improve the detection rate of early esophageal cancer and precancerous lesions, worthy of clinical application.