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压制中药片剂,粘冲是时常遇到的困难之一,笔者结合生产实践,试就粘冲问题,作初步探讨。(一)因素分析粘冲因素多种,主要归类如下。1.颗粒中药物或添加剂含有低熔点(低软化点)成分。这些成分未与其他组分混合均匀,压片时,受压缩热作用,而熔化或软化,解压后粘结于铳的表面。“腰痛片”、“小活络片”处方中均含有低软化点的乳香没药(我们曾取样测得乳香没药的软化点分别为78℃和87℃),它们与其他组分搅拌不均
To suppress Chinese medicine tablets, sticking red is one of the difficulties encountered often, the author combines production practices, trials on the sticking red question for preliminary discussion. (I) Factor Analysis There are many kinds of sticking and blunt factors, which are mainly categorized as follows. 1. The drug or additive in the granule contains a low melting point (low softening point) component. These components are not evenly mixed with other components, and when compressed, they are subjected to heat of compression, melted or softened, and decompressed to adhere to the surface of the crucible. “Lu Yao Tablet” and “Xiao Huolong Tablets” all contain low-softening point frankincense myrrh (we have sampled to measure the softening point of frankincense myrrh, which is 78 °C and 87 °C, respectively), and they are not evenly mixed with other components.