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扰动角关联方法1968年首次应用于生物学研究,现更多地用来研究生物大分子构型的变化、探测液态分子的旋转关联时间、测定金属离子结合生物大分子的离解常数及结合位置等,为生物学研究提供了有用的数据,并正在发展成为一种生物物理学的新方法,将在分子生物学及药物代谢动力学中显示其优越性。
The perturbation angle correlation method was firstly applied to biology research in 1968, and is used to study the change of configuration of biological macromolecules, to detect the rotation related time of liquid molecules, to determine the dissociation constant and binding position of metal ions in combination with biological macromolecules , Provides useful data for biological research and is evolving into a new method of biophysics that will demonstrate its superiority in molecular biology and pharmacokinetics.