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目前使用的乙肝血源疫苗,来源有限,成本高,所以,寻求来源充足、免疫效果好的基因疫苗是我国迫切需要解决的问题。1986年12月,我们对Amgen公司和Smith公司生产的酵母基因疫苗的免疫原性进行了对比观察,为我国选购和引进有关技术研制基因疫苗提供资料。
The currently used hepatitis B blood-borne vaccine has limited sources and high costs. Therefore, it is urgent for China to seek gene vaccines with sufficient source and good immunization effects. In December 1986, we compared the immunogenicity of the yeast gene vaccines produced by Amgen and Smith, and provided information for our country to purchase and introduce the technology to develop gene vaccines.