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本文总结84例小儿恶性淋巴瘤临床特点。男女性别比为5.5∶1。发病年龄高峰:HD5~9岁;NHL6~10岁。NHL比HD病程短。浅表淋巴结肿大为首发者占72.6%,结外首发只见NHL,占48.8%。NHL中高度恶性占77.1%,诊断时即为广泛播散期者占53.5%,其中白血病化占18.6%,脑膜侵犯占11.6%。提示用强烈化疗方案可提高小儿NHL的疗效和生存率。
This article summarizes the clinical features of 84 cases of pediatric malignant lymphoma. Sex ratio for men and women is 5.5: 1. Peak age of onset: HD5 ~ 9 years old; NHL6 ~ 10 years old. NHL shorter than the duration of HD. Superficial lymph nodes as the first episode accounted for 72.6%, the first episode of extranodal NHL, accounting for 48.8%. In NHL, 77.1% were highly malignant and 53.5% were disseminated at diagnosis. Among them, leukemia accounted for 18.6% and meningeal invasion accounted for 11.6%. Tip with intensive chemotherapy can improve the efficacy and survival of children with NHL.