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目的探讨丘脑出血继发肾上腺皮质功能减退症的临床特点。方法回顾性分析我院收治8例丘脑出血继发肾上腺皮质功能减退症患者的临床资料。结果 8例患者在丘脑出血治疗缓解后,突然出现病情加重,复查头颅CT未发现新鲜出血灶,或原出血灶变大,但患者血糖水平较入院时明显降低,电解质紊乱,血中促肾上腺激素和24 h尿17羟-皮质类固醇降低。激素替代治疗后所有患者均痊愈出院。结论丘脑出血病情突然加重时,应考虑继发肾上腺皮质功能减退可能,应及时确诊并给予激素替代治疗,有利于病情恢复。
Objective To investigate the clinical features of sub-adrenal hypofunction after thalamic hemorrhage. Methods The clinical data of 8 patients with sub-adrenocortical hypofunction who were treated with thalamic hemorrhage in our hospital were retrospectively analyzed. Results After the treatment of thalamic hemorrhage, 8 patients were suddenly exacerbated. There were no fresh hemorrhagic lesions or enlarged hemorrhagic lesions in the head CT. However, the blood glucose levels of the 8 patients were significantly lower than those on admission, and electrolyte imbalance, adrenocorticotropic hormone And 24 h urinary 17 hydroxy-corticosteroids decreased. All patients were cured after hormone replacement therapy. Conclusions When the condition of thalamic hemorrhage suddenly aggravates, the possibility of secondary adrenocortical dysfunction should be considered. It should be promptly diagnosed and treated with hormone replacement therapy, which is beneficial to the recovery of the disease.