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【目的】通过对兔面神经喷灌式液氮冷冻后进行电生理研究,探讨面神经冷冻损伤后功能的恢复情况。【方法】新西兰大白兔36只,按观察时限不同随机分为术后即刻、1周、2周、4周、8周及12周组。以液氮喷灌冷冻右侧面神经,而以左侧面神经为正常对照组。到观察时限进行两侧面神经电生理检测,对电生理检测结果进行配对t检验。【结果】即刻、1周、2周组刺激右侧面神经均未诱导出口轮匝肌复合动作电位。4周组、8周组、12周组:最大波幅及传导速度随观察时间的延长,其恢复逐渐增加,阈强度及潜伏期,随观察时间延长逐渐降低,但至12周后最大波幅及传导速度仍与正常组比较有统计学差异(P<0.05)。【结论】面神经在液氮冷冻损伤后,早期功能丧失,随着时间的延长,能再生而恢复功能。
【Objective】 To investigate the recovery of facial nerve after freezing injury by electrophysiological study of facial nerve after liquid nitrogen freezing. 【Method】 Thirty-six New Zealand white rabbits were randomly divided into immediate postoperative, 1 week, 2 weeks, 4 weeks, 8 weeks and 12 weeks according to the observation time. Frozen right facial nerve was sprayed with liquid nitrogen, while the left facial nerve was normal control group. To observe the time limit on both sides of facial nerve electrophysiological test, electrophysiological test results were paired t test. 【Results】 Immediate, 1 week, 2 weeks stimulation of right facial nerve did not induce exit orbicularis muscle compound action potentials. After 4 weeks, 8 weeks and 12 weeks, the maximum amplitude and conduction velocity gradually increased with the prolongation of observation time. The threshold intensity and latency decreased gradually with the prolongation of observation time. However, the maximum amplitude and conduction velocity Still with the normal group was statistically significant (P <0.05). 【Conclusion】 After the facial nerve is frozen in liquid nitrogen, the early loss of function, with the extension of time, can regenerate and restore function.