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消化道恶性肿瘤术后复发率较高,传统静脉化疗、肠腔内灌注化疗等效果不佳,且不良反应大。近年来国内外学者开始对腹腔化疗进行研究,并取得了一些进展,但对术后早期腹腔化疗是否影响吻合口愈合等问题,仍存在争议。对于腹腔化疗药联合哪些药物可使化疗效果更佳,仍无统一的标准。本研究对目前腹腔化疗的有关问题特别是腹腔化疗的有效性及安全性等进行综述。
Gastrointestinal malignant tumor recurrence rate is higher, the traditional intravenous chemotherapy, intestinal perfusion chemotherapy ineffective, and adverse reactions. In recent years, domestic and foreign scholars began to study the peritoneal chemotherapy, and made some progress, but whether postoperative early peritoneal chemotherapy affect anastomotic healing and other issues, there is still controversy. For the combination of intraperitoneal chemotherapy drugs which can make the chemotherapy effect is better, there is no uniform standard. This study summarizes the current issues related to intraperitoneal chemotherapy, especially the efficacy and safety of intraperitoneal chemotherapy.