论文部分内容阅读
美《医学论坛报》第21卷第22期(1980年)报道:日本千叶大学古川医生及其同事用经导管动脉栓塞疗法,治疗8例不能手术的肝癌病人,其中2例病人恢复正常的生活。古川在日本胃肠外科协会会议上说,单独进行化疗、免疫疗法或手术,对于肝癌已发展至两叶或并发肝硬化的患者无何价值。在栓塞疗法后,再作免疫和化学疗法,8例中有6例病人生存1～11个月。病人年龄为40～61岁,包括4例肝细胞瘤,1例在手术切除后复发,源自胆囊的肝转移癌、胃和乙状结肠曲的肝转移癌各1例。经血管造影证实肿瘤大小并定位后,病人动脉注射血管紧张素及丝裂霉素C。用凝胶泡沫为栓塞剂,阻断肝动脉,此肝动脉约可输送90％营养。然后合并应用免疫和化学治疗。血管造影表明,肿瘤血管有部分受到损害,未受损害正常的血管继后又重新通畅。8例中有7例表明有抗瘤作用,甲胎蛋白值降低20％到30％。比较成功的是3例肝细胞癌病人,其中2例出
US Medical Tribune, Vol. 21, No. 22 (1980) reported: Dr. Furukawa from the Chiba University in Japan and colleagues used transcatheter arterial embolization to treat 8 cases of inoperable liver cancer patients, of which 2 patients returned to normal. life. At the meeting of the Japan Society of Gastrointestinal Surgery, Furukawa stated that chemotherapy alone, immunotherapy or surgery alone is of no value for patients with hepatocellular carcinoma who have developed two-lobe or concurrent cirrhosis. After embolization therapy, immunization and chemotherapy were performed, and 6 of 8 patients survived for 1 to 11 months. The patient’s age ranged from 40 to 61 years, including 4 cases of hepatoma, 1 case of recurrence after surgical resection, 1 case of liver metastases from the gallbladder, and 1 case of hepatic metastases from the stomach and sigmoid curve. After angiography confirmed the size and location of the tumor, the patient was given an arterial injection of angiotensin and mitomycin C. Using a gel foam as an embolic agent to block the hepatic artery, this hepatic artery can deliver approximately 90% of its nutrition. Then combine immunotherapy and chemotherapy. Angiography shows that some of the tumor’s blood vessels are damaged, and undamaged normal blood vessels are re-opened. Seven of the eight cases showed anti-tumor effects, and the alpha-fetoprotein value decreased by 20% to 30%. The more successful patients were 3 cases of hepatocellular carcinoma, 2 cases of which