本文对 13例皮肤 LP和 10例口腔粘膜 LP作 DIF检查,在真皮上部或粘膜下发现细胞样体染色,阳性率分别为77％和60％,有助于本病的诊断。进一步对皮肤或口腔粘膜LP各 8例和皮肤淀粉样变 3例的标本,用单抗 AE_1 和 AE_3 作 IIF检查,DIF 示细胞样体阳性的 LP标本全部被单抗 AE_1 或AE_3 染色。相反,阳性染色的皮肤淀粉样变和细胞样体阴性的 LP标本不能被上述单抗着染。本文就此结果的临床意义及发病机理进行讨论。 In this paper, 13 cases of skin LP and 10 cases of oral mucosa LP for DIF examination, found in the dermis or submucosal cell-like body staining, the positive rates were 77% and 60%, contribute to the diagnosis of the disease. Furthermore, 8 specimens of skin or oral mucosa LP and 3 samples of skin amyloidosis were examined by IIF with McAbs AE_1 and AE_3, respectively. All the LP specimens positive for cell-like bodies were stained with McAb AE_1 or AE_3. In contrast, positively stained skin amyloidosis and cell-like negative LP specimens could not be stained with the above mAb. This article discusses the clinical significance and pathogenesis of this result.