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胰岛素抵抗是代谢综合征的核心,后者包括冠心病、高血压病、2型糖尿病、肥胖等一组临床疾病。抵抗素(resistin)作为一种脂肪细胞因子被认为可导致胰岛素抵抗,可能是联系肥胖、胰岛素抵抗及糖尿病的重要信号分子。本研究应用果糖诱导制作胰岛素抵抗高血压动物模型,观察罗格列酮
Insulin resistance is the core of the metabolic syndrome, which includes coronary heart disease, hypertension, type 2 diabetes, obesity and other clinical diseases. As an adipocytokine, resistin is thought to cause insulin resistance and may be an important signaling molecule that links obesity, insulin resistance and diabetes. In this study, fructose-induced insulin resistance in the production of animal models of hypertension, observation of rosiglitazone