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目的:分析X综合征患者的时域指标,探讨自主神经功能与X综合征之间的关系。方法:对X综合征组、冠心病组、对照组患者进行24h动态心电图监测,分析测定24h连续正常R-R间期的标准差、24h连续每5min节段的正常R-R间期的标准差的平均数、24h连续每5min节段的正常R-R间期的标准差、24h连续正常R-R间期差值均方的平均根(r MSSD)、2个相邻R-R间期互差>50ms的心跳数占所分析信息间期心搏数的百分比(PNN50)等指标情况。结果:X综合征组、冠心病组各指标与对照组比较,除冠心病组r MSSD、PNN50P<0·01以外,其余均P<0·05;X综合征组、冠心病组比较差异无统计学意义。结论:X综合征患者存在心血管自主神经系统功能调节不平衡现象,以交感神经活动占优势。
Objective: To analyze the time-domain index of patients with syndrome X and to explore the relationship between autonomic nervous function and syndrome X. Methods: The patients of syndrome X, coronary heart disease and control group were monitored by Holter monitoring 24h, the standard deviation of 24h continuous normal RR interval and the standard deviation of normal RR interval of 24h continuous every 5min were analyzed , The standard deviation of the normal RR interval for every 5 min in 24 h, the average root mean square of the difference in 24 h continuous normal RR interval (r MSSD), the number of heartbeats with difference of> 50 ms between two adjacent RR intervals Analyze the percentage of interphase heart rate information (PNN50) and other indicators. Results: Compared with the control group, all the indexes in syndrome group X and coronary heart disease group were all significantly lower than those in control group (r MSSD, PNN50P <0.01) Statistical significance. Conclusion: There is imbalance in functional regulation of cardiovascular autonomic nervous system in patients with syndrome X, and sympathetic activity predominates.