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目的 探讨睡眠呼吸暂停综合征对生存质量的影响因素。方法 采用WHOQOL -BREF生存质量量表对 2 12例OSAS患者进行生存质量测评 ,比较嗜睡、睡眠质量、慢性病对患者生存质量的影响和经鼻持续气道正压通气 (nCPAP)治疗后的改变。结果 OSAS患者生存质量生理领域、心理领域得分均值均为嗜睡组低于不嗜睡组、睡眠质量差组低于睡眠质量好组 (P均 <0 0 1) ;生理、心理、社会、环境四个领域的评分均为伴有慢性病组低于不伴有慢性病组 (P <0 0 1和P <0 0 5 ) ;nCPAP治疗后生存质量总分比治疗前明显提高 (P <0 0 1) ,嗜睡评分和睡眠质量评分比治疗前有明显降低 (P <0 0 1)。结论 OSAS患者的嗜睡、低睡眠质量及慢性病是影响生活质量的因素 ,nCPAP治疗能改善白天嗜睡和睡眠质量 ,提高患者生存质量。
Objective To explore the influential factors of quality of life in sleep apnea syndrome. Methods The quality of life of 2 12 OSAS patients was evaluated by WHOQOL -BREF Quality of Life Scale. The effects of lethargy, sleep quality and chronic diseases on the quality of life and the changes after nCPAP were compared. Results The OSAS scores of quality of life in both physical and psychological domains were lower in sleepiness group than those in non-sleepiness group and worse in sleep quality group (P <0.01), and four in physical, psychological, social and environmental quality (P <0.01 and P <0.05). The total score of quality of life after nCPAP treatment was significantly higher than that before treatment (P <0.01) Somnolence scores and sleep quality scores were significantly lower than before treatment (P <0.01). Conclusion Sleepiness, low sleep quality and chronic diseases in OSAS patients are the factors that affect the quality of life. NCPAP treatment can improve daytime sleepiness and sleep quality, and improve the quality of life of patients.