[目的]提高对病因不明,普通治疗效果无效的结节红斑的疗效。[方法]挑选结节红斑患者中无明确病因,对普通治疗无反应,在结核菌素试验呈明显阳性者进行抗结核治疗。[结果]18例患者经抗结核治疗,结节红斑的发作频度及强度明显改善。[结论]对部分病因不明,结核菌素试验呈明显阳性者的结节红斑患者行抗结核治疗可以改善其病情。 [Objective] To improve the etiology of unknown, the general effect of treatment of nodular erythema curative effect. [Method] There was no definite etiology in selecting erythema nodosum, no reaction to common treatment, anti-TB treatment in patients with positive tuberculin test. [Result] The frequency and intensity of erythema nodosum in the eighteen patients were significantly improved after anti-TB treatment. [Conclusion] Some patients with erythema nodosum who have unknown etiology and tuberculin test showed positive anti-TB treatment can improve their condition.