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脂肪组织来源干细胞属于成体干细胞范畴,具有多能分化潜能,有分化成不同细胞系的能力。它较容易从脂肪组织中获得,并能在体外扩增,在再生医学方面具有广阔的应用潜力。目前,世界范围内,利用人脂肪组织来源干细胞进行治疗的多项临床试验正在开展。在眼科方面,于角膜病、视网膜病和眼眶整形方面都进行了基础及应用研究,并得到了较为理想的结果。由于其干细胞固有特点,其应用存在一些风险,需对其安全性进行进一步研究并在政府的监管下开展临床研究,以期确定脂肪组织来源干细胞的长期安全性和有效性。
Adipose tissue-derived stem cells belong to the category of adult stem cells, have pluripotency and have the ability to differentiate into different cell lines. It is easier to obtain from adipose tissue and can be expanded in vitro and has broad potential in regenerative medicine. Currently, many clinical trials using human adipose tissue-derived stem cells are undergoing treatment worldwide. In the field of ophthalmology, corneal disease, retinopathy and orbital plastic surgery have carried out the basic and applied research, and obtained the more satisfactory results. Because of its inherent characteristics of stem cells, there are some risks in its application. It is necessary to conduct further research on its safety and carry out clinical studies under the supervision of the government in order to determine the long-term safety and effectiveness of adipose tissue-derived stem cells.