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采用左侧精索静脉主干结扎和左肾静脉部分结扎诱导SD 大鼠精索静脉曲张,并对其睾丸、附睾的组织学进行了研究。结果表明:精索静脉曲张所致睾丸曲细精管病变为双侧性,病变曲细精管与正常曲细精管成片交错存在,呈典型的“斑点样“表现。最主要的病变是精子成熟障碍,其次为精子细胞及精母细胞提前释放入管腔;睾丸病变程度与静脉曲张程度无相关关系(P>0.05);左右睾丸病变程度也无显著差异(P>0.05);精索静脉主干结扎与肾静脉部分结扎所致睾丸病变相同(P>0.05),且两者分别与对照组比较有显著差异。(P<0.01)。光镜下附睾上皮无明显异常。
The left varicocele ligation and partial ligation of the left renal vein were used to induce the varicocele of SD rats. The histology of the testis and epididymis were studied. The results showed that: varicocele caused by testicular seminiferous tubules lesions bilateral, lesions of seminiferous tubules and normal seminiferous tubules into pieces staggered, showing a typical “spot-like” performance. The main pathological changes were sperm maturation disorder, followed by early release of spermatids and spermatocytes into the lumen. There was no correlation between the degree of testicular lesions and varicose veins (P> 0.05). There was no significant difference in the degree of testicular lesions between the two groups (P> 0.05). The main ligation of the varicocele was the same as that of the testicular lesions caused by partial ligation of the renal vein (P> 0.05), and both of them were significantly different from the control group. (P <0.01). Light microscope epididymal epithelial no obvious abnormalities.