作者选择17例有典型雷诺氏现象的女性患者用硝苯吡啶进行双盲交叉对照试验。他们的年令为76～67岁,平均病程为9.9年,5例为特发性的、11例继发于系统性硬化病、1例继发于系统性红斑狼疮。15例发作时痛,6例有复发性指(趾)端溃疡,1例有偏头痛,4例有胸痛(除外冠状血管痉挛)。6例以前用各种血管舒张药无效,3例对颈 The authors selected 17 women with typical Raynaud’s phenomenon to perform a double-blind crossover study with nifedipine. Their age ranged from 76 to 67 years with an average duration of 9.9 years, 5 were idiopathic, 11 were secondary to systemic sclerosis and 1 was secondary to systemic lupus erythematosus. Fifteen had pain at onset, six had recurrent nail-tip ulcers, one had migraine, and four had chest pain (except for coronary vasospasm). Six cases were previously ineffective with various vasodilators and three cases with neck