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A new triterpenoid saponins,raddeanoside R_(19)(1) was isolated from the rhizome of Anemone raddeana Regel.The effects of raddeanoside R_(19) on superoxide generation in human neutrophil were evaluated.The compound suppressed the superoxide generation induced by N-formyl-methionyl-leucyl-phenylalanine(fMLP),phorbol 12-myristate 13-acetate(PMA) and arachidonic acid(AA) in a different concentration-dependent manner.
A new triterpenoid saponins, raddeanoside R_ (19) (1) was isolated from the rhizome of Anemone raddeana Regel. The effects of raddeanoside R_ (19) on superoxide generation in human neutrophil were as the compounds suppressed the superoxide generation induced by N- formyl-methionyl-leucyl-phenylalanine (fMLP), phorbol 12-myristate 13-acetate (PMA) and arachidonic acid (AA) in a different concentration-dependent manner.