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对常规抗甲状腺治疗耐药或对抗甲状腺药物过敏的患者,锂有肯定的抗甲状腺作用,碳酸锂与抗甲状腺药物联合应用常常作为某些严重甲亢患者的快速术前准备。作者报告2例严重甲亢患者,均为女性,因甲亢反复发作,症状严重,故急需作手术治疗。术前给予他巴唑和碳酸锂治疗(剂量为他巴唑40和60mg/天,碳酸锂1050和900mg/天),2例均在治疗的第12天时获得正常甲状腺功能状态。治疗过程中测得血清锂含量分别为0.33～0.51mEq/L和0.69～0.9 mEq/L,除第2例有震颤加重,不自主活动外,余未见副作
Lithium has a positive antithyroid effect in patients who are resistant to conventional antithyroid drugs or allergic to thyroid drugs. The combination of lithium carbonate and anti-thyroid drugs is often used as a quick preoperative preparation for some patients with severe hyperthyroidism. The authors report 2 patients with severe hyperthyroidism, all women, because of recurrent hyperthyroidism, severe symptoms, it is in urgent need of surgical treatment. Metabazole and lithium carbonate were given preoperatively (at doses 40 and 60 mg / day for methimazole and 1050 and 900 mg / day for lithium carbonate), and 2 patients achieved normal thyroid function status on the 12th day of treatment. The measured serum lithium levels during treatment were 0.33 ~ 0.51mEq / L and 0.69 ~ 0.9 mEq / L, in addition to the second case of tremor aggravated, involuntary activities, I did not see the deputy