现已发现,各年龄组小儿血清血管紧张素转化酶(ACE)的活性无显著差异,紫绀和非紫绀型先天性心脏病(CHD)患儿血清ACE活性亦无差异。作者研究了CHD儿童血清ACE的活性。病人和方法作者调查了46例CHD儿童(男28例,女18例),年龄1个月至14.5岁。患儿未接受心脏治疗,也未发生充血性心力衰竭。由于肾灌注异常可影响肾素—血管紧张素—醛固同酮系统,故主动脉缩 It has been found that there is no significant difference in the serum ACE activity between children of all ages and no difference in serum ACE activity between children with cyanotic and non-cyanotic congenital heart disease (CHD). The authors studied serum ACE activity in CHD children. Patients and Methods The authors investigated 46 CHD children (28 males and 18 females) aged 1 month to 14.5 years. Children did not receive heart treatment nor congestive heart failure. As renal perfusion abnormalities can affect the renin-angiotensin-aldosterone system, aortic contraction