目的探讨再次肺切除治疗肺癌及胸膜肿瘤肺浸润的价值。方法回顾6例肺癌及1例胸膜肉瘤肺浸润患者再次手术治疗的资料,分析手术难度及术后恢复情况并总结治疗经验,随访分析全组病例生存情况。结果除胸膜肉瘤外其余6例肺癌患者均为完全切除病灶,无术中及围术期死亡。7例胸膜粘连均严重,尤其肺门处肿瘤生长、浸润严重,3例患者肺门大血管破裂出血500 ml以上。手术时间和术中出血量明显超出初次手术(P=0.000)。术后发生心、肺功能不全各1例,短期支气管胸膜瘘、伤口感染各1例。全组1年、2年生存率分别为42.9%和14.3%,肺癌组1年、2年生存率分别为50.0%和16.7%。结论虽然肺部肿瘤再次手术的难度和风险增大,但其成功率仍然很高,只要掌握好手术指征再次手术仍然能够获得满意疗效。 Objective To investigate the value of lung resection for pulmonary invasion in lung cancer and pleural tumor. Methods Six cases of lung cancer and one case of pulmonary infiltrates with pleural sarcoma were retrospectively reviewed. The surgical difficulty and postoperative recovery were analyzed and the treatment experience was summarized. The survival of the patients was followed up. Results In addition to pleural sarcoma, the remaining 6 cases of lung cancer patients were completely resected lesions, no intraoperative and perioperative deaths. Seven cases of pleural adhesions were serious, especially in the hilar tumor growth, severe infiltration, hilar large vessels in 3 patients with bleeding 500 ml or more. The operation time and intraoperative blood loss significantly exceeded the initial surgery (P = 0.000). Postoperative heart and lung dysfunction in 1 case, short-term bronchopleural fistula, wound infection in 1 case. The overall 1-year and 2-year survival rates were 42.9% and 14.3% respectively. The 1-year and 2-year survival rates of lung cancer group were 50.0% and 16.7%, respectively. Conclusion Although the difficulty and risk of reoperation of pulmonary neoplasm increased, its success rate is still very high. As long as the indications of operation are reoperated, satisfactory curative effect can still be obtained.