论文部分内容阅读
目的了解极低出生体质量儿童(VLBWI)学龄期的生存质量状况及其影响因素,为早期临床干预提供理论依据。方法采用横断面病例对照研究设计。以儿童生存质量量表体系的普适性核心量表(PedsQLTM4.0)对235名就读主流学校的VLBWI和396名正常出生体质量儿童(NBWI)的家长进行问卷调查,量表共23个条目,包括4个方面,即生理功能、情感功能、社会功能、角色功能。通过计算量表总分和各领域的得分分析VLBWI学龄期的生存质量及其影响因素。结果调查的631个家庭中570个家庭完成问卷,应答率90.3%。VLBWI组年龄(9.6±2.5)岁,出生体质量1 004～1 498 g[(1 201±279)g];NBWI组年龄(9.7±3.1)岁,出生体质量2 512～3 955 g[(3 216±435)g]。VLBWI组情感功能得分[(73.12±16.67)分]、角色功能得分[(70.43±20.67)分]及生存质量总分[(75.98±17.53)分]低于NBWI组[分别为(79.16±17.22)分、(77.43±19.63)分和(80.21±17.29)分],差异均有统计学意义(Pa<0.05)。运用多元线性回归分析结果显示,母亲学历高的VLBWI生存质量较高,新生儿期患颅内出血、早产儿视网膜病变的VLBWI生存质量较低。结论 VLBWI生存质量低于NBWI,在情感功能及角色功能方面尤为明显,母亲学历水平和新生儿期病理生理状态是其重要的影响因素,应予监测和进行相应干预。
Objective To understand the quality of life of the very low birth weight children (VLBWI) in school age and its influencing factors, and to provide a theoretical basis for early clinical intervention. Methods A cross-sectional case-control study was designed. A total of 235 parents of VLBWI and 396 children with normal birth weight (NBWI) from 235 primary school schools were surveyed using the PPSQL (PedsQLTM 4.0), a total of 23 items , Including four aspects, namely physiological function, emotional function, social function, role function. The quality of life and its influencing factors in VLBWI school-age were analyzed by calculating the total scores of scales and scores in each field. Results The survey of 570 families in 631 families completed the questionnaire, the response rate of 90.3%. The VLBWI group was (9.6 ± 2.5) years old with a birth weight of 1 004-1 498 g [(1 201 ± 279) g]; NBWI group (9.7 ± 3.1) years old with a birth weight of 2 512-3 955 g [ 3 216 ± 435) g]. The scores of emotional function (73.12 ± 16.67), role function score (70.43 ± 20.67) and quality of life score (75.98 ± 17.53) in VLBWI group were lower than those in NBWI group (79.16 ± 17.22, (77.43 ± 19.63) points and (80.21 ± 17.29) points respectively, the difference was statistically significant (Pa <0.05). The results of multivariate linear regression analysis showed that the high quality of life of VLBWI with high education of mother, intracranial hemorrhage in neonatal period, low quality of life of VLBWI in retinopathy of prematurity. Conclusion The quality of life of VLBWI is lower than that of NBWI, especially in the aspects of emotional function and function. The level of maternal education and the pathophysiological status in neonatal period are important factors that should be monitored and intervened accordingly.