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BCG膀胱内灌注治疗表浅膀胱癌或经尿道电切后预防复发常见的副作用为膀胱刺激症状,血尿或附睾炎,严重全身反应较少见,但不容忽视的是BCG局部治疗可致威胁生命的血循播散,称为“BCG炎”(BCGitis)。作者在169例用BCG(150mg/次)膀胱内灌注治疗表浅肿瘤时遇见5例(30/0),患者均有支所管肺部病变和内芽肿性肝炎,4例发生于治疗早期(3～8次灌注后),另一例则在2年的灌注治疗结束以后半年才发生,骨髓穿制发现多发性肉芽肿(上皮样细胞结节内有郎格氏巨细胞),3例灌注时的损伤和出血导致BCG血循播散,症状为灌注后1天寒战,高热(可达39℃以上),持续不退,白细胞
BCG intravesical instillation for the treatment of superficial bladder cancer or transurethral resection of the common side effects of bladder irritation, hematuria or epididymitis, severe systemic reactions are rare, but can not be ignored is that BCG topical treatment can be life-threatening Circulation of blood, known as “BCG inflammation” (BCGitis). The authors met with 5 cases (30/0) of 169 patients treated with intravesical instillation of BCG (150 mg / time) for superficial tumors with branching lung disease and endogenous budding hepatitis and 4 in the early stages of treatment 3-8 times after perfusion) and the other one six months after the end of 2-year perfusion therapy. Multiple granulomas were found in the bone marrow system (Lange & apos; s cells in the epithelial cell nodules) Of the injury and bleeding lead to BCG blood dispersal, symptoms 1 day after perfusion chills, high fever (up to 39 ℃ above), persistent, white blood cells