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目的:分析轻度胃肠炎伴发婴幼儿良性惊厥(BICE)的临床特点和预后。方法:对我院收治的32例BICE住院患儿进行临床观察和随访。结果:32例患儿发病年龄最小8个月,最大28个月。胃肠道症状出现2 d内发生惊厥28例(87.5%),持续时间<5 min;发作形式为全身强直-阵挛发作29例(90.6%),局限性发作泛发为全面型发作3例(9.4%)。惊厥发作间期患儿脑电图、脑影像学、血生化、脑脊液检查均正常。大便轮状病毒阳性组和阴性组在BICE的发病年龄、发生时间、发作次数及丛集发作时间比较差异均无统计学意义(P>0.05)。结论:BICE患儿消化系统表现较轻微,惊厥成簇发作,预后良好。临床上以对症治疗为主,应避免不必要的检查和过度的药物治疗。
Objective: To analyze the clinical features and prognosis of mild gastroenteritis associated with benign convulsion (BICE) in infants and young children. Methods: 32 cases of BICE hospitalized in our hospital were observed and followed up. Results: The incidence of 32 cases of children at least 8 months, up to 28 months. There were 28 cases (87.5%) of convulsions in gastrointestinal symptoms within 2 days, duration <5 minutes, 29 cases (90.6%) of generalized tonic-clonic seizures, and 3 cases of generalized seizures (9.4%). Seizures in children with interictal EEG, brain imaging, blood biochemistry, cerebrospinal fluid were normal. Stool rotavirus positive group and negative group in BICE age of onset, time of onset, the number of seizures and cluster attack time differences were not statistically significant (P> 0.05). Conclusions: The digestive system of BICE children showed mild and cluster convulsion, and the prognosis was good. The main symptomatic treatment clinics, should avoid unnecessary checks and excessive medication.