科学(Science)杂志曾多次将生物钟的研究评为“可能改变人类对自然的认识,从而产生重大社会和经济效益的、有重大突破的研究领域”,而以此为基础的肿瘤时辰治疗学(chronothera-py)也逐渐成为肿瘤基础和临床研究的新热点。目前肿瘤时辰治疗在减少不良反应,增加最大耐受量,提高疗 Science magazine has repeatedly named the study of the biological clock as a “research area that has a major breakthrough in research that may change the human understanding of nature and thereby generate major social and economic benefits.” Based on this, (chronothera-py) has also gradually become the new focus of tumor and clinical research. The current treatment of tumor in reducing adverse reactions, increase the maximum tolerated dose, improve treatment