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目的为血栓前状态的血标本检测提供细微、动态的细胞学行为指标。方法本研究采用“清华同方”高放大率显微系统（ＴＨＭＩ—ＵＰ型，可放大１６０００倍）对ＥＬＴ（优球蛋白溶解时间）延迟、组织纤溶酶原激活物（ｔ－ＰＡ）含量减少、纤溶酶原激活物抑制物（ＰＡＩ）及ａ２纤溶抑制物活性增高的标本进行检测。结果可见明显的红细胞聚集、血小板聚集和循环内皮细胞（ＣＥＣ），这些因子对血栓的最终形成具有重要意义。结论纤溶蛋白溶解系统各项指标的检测在临床上应用广泛，常用来反映机体血栓前状态，其特异性一直是关注焦点，本实验利用高放大率显微系统从分析活血细胞的行为出发，为血栓前状态的血标本检测提供了更微细的细胞学行为特征。
The purpose is to provide subtle, dynamic cytological behavioral indicators for the detection of prethrombotic blood samples. Methods In this study, we used a “high-magnification” (THMI-UP) microscopy system (THMI-UP, magnification 16000 times) to delay the ELT (euglobulin lysis time) and reduce the content of tissue plasminogen activator , Plasminogen activator inhibitor (PAI) and a2 fibrinolysis inhibitor increased activity of specimens were detected. The results showed significant erythrocyte aggregation, platelet aggregation and circulating endothelial cells (CEC), which are important for the ultimate formation of thrombi. Conclusion The detection of various indexes of fibrinolytic system has been widely used in clinical practice. It is often used to reflect the prethrombotic state of the body. The specificity of fibrinolytic system has been the focus of attention. In this experiment, the high magnification microscopy system was used to analyze the behavior of activated blood cells. Provides a more subtle cytological profile for the detection of pre-thrombotic blood samples.