对疟疾时的贫血,过去常以机械性溶血或偶尔因抗-Ⅰ抗体的存在来解释,而血小板减少和淋巴细胞减少的机理则仍不明确。Wells曾在恶性疟和间日疟患者中发现淋巴细胞毒抗体,于15℃时其阳性率在间日疟和恶性疟患者中分别达98%和95%。本文作者用微量淋巴细胞毒技术,对23例各种疟疾患者进行了细胞毒抗体研究。在7例未接受输血的疟疾病人中,发现不同程度的多特异性细胞毒抗体,有的细胞 Anemia in malaria was often explained by mechanical hemolysis or the occasional presence of anti-I antibodies, and the mechanism of thrombocytopenia and lymphopenia remains unclear. Wells have found lymphocytic antibodies in patients with falciparum malaria and vivax malaria and have a positive rate of 98% and 95%, respectively, at 15 ° C in patients with P. vivax and falciparum malaria. The authors used cytotoxicity to detect cytotoxicity in 23 malaria patients. In seven cases of malaria patients who did not receive blood transfusions, they found different degrees of multispecific cytotoxic antibodies, some of them