遗传性多发性骨软骨瘤为先天性骨骼发育异常,有明显的家族遗传史。我们遇到一家四代20例全为男性(见系谱),除第Ⅳ代的Ⅳ_(10)、Ⅳ_(11)两例是经母亲遗传外,其余18例都是经父亲遗传。女性虽无1人罹病,但女Ⅲ_6所生3人中男性2人患病(Ⅳ_(10)、Ⅳ_(11))。患者都以明显无误的骨性包块及明显畸形为根据,经X光摄片证实2例。已死 Hereditary multiple osteochondroma is congenital skeletal dysplasia with a distinct family history. We encountered a fourth generation of 20 cases of all males (see pedigrees). Except for the IV IV generation IV_(10) and IV_(11) cases, which were inherited by the mother, the remaining 18 cases were inherited by the father. Although none of the women reported rickets, 2 out of 3 females born in female III_6 were ill (IV_(10), IV_(11)). The patients were all confirmed by X-ray radiography based on the apparent bony mass and obvious malformation. Dead