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目的对三磷酸肌醇受体在妊娠期高血压患者胎盘组织中的表达以及临床意义进行分析探讨,为今后的临床诊治工作提供可靠的参考依据。方法抽取在2011年1月至2012年12月间本院收治的正常妊娠孕妇和妊娠期高血压患者各56例,对其展开三磷酸肌醇受体表达水平检测,并对检测结果进行对比分析。结果妊娠高血压患者胎盘组织中三磷酸肌醇受体的表达强度较正常妊娠组高(P<0.05)。结论在妊娠期高血压患者胎盘组织中三磷酸肌醇受体呈现高表达,对其展开检测能够为临床诊治工作提供可靠信息,值得关注。
Objective To investigate the expression and clinical significance of inositol 1,4,5-trisphosphate receptor in placental tissue of patients with gestational hypertension and provide a reliable reference for future clinical diagnosis and treatment. Methods Fifty-six normal pregnant women and gestational hypertensive patients admitted to our hospital from January 2011 to December 2012 were enrolled in this study. The expression of inositol 1,4,5-trisphosphate receptor was detected and the results were compared . Results The expression of inositol 1,4,5 - trisphosphate receptor in placental tissue of patients with pregnancy - induced hypertension was higher than that of normal pregnancy group (P <0.05). Conclusion The placental tissue of hypertensive patients with gestational hypertension showed high expression of inositol 1,4,5-triphosphate receptor, and its detection can provide reliable information for clinical diagnosis and treatment, which deserves attention.