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作者将70例慢性粒细胞白血病(慢粒)分为两组。A组:52例,男29、女23例,年龄11~47岁,中位年龄27岁,均为慢粒慢性期;B 组:18例,男11、女7例,年龄13~42岁,中位年龄28岁,此组包括慢粒加速期、急变期、急变经治疗后缓解期及继发性慢性期(出现 Ph′阳性的急淋)。骨髓移植前6天或5天给予大剂量环磷酰胺60mg/kg/d,术前4~2天给予全身放射,总量10Gy 分5次或总量12Gy 分6次进
The authors divided 70 patients with chronic myeloid leukemia (CML) into two groups. A group: 52 cases, 29 males and 23 females, aged from 11 to 47 years, median age 27 years old, are chronic chronic phase; B group: 18 cases, 11 males and 7 females, aged 13 to 42 years , The median age was 28 years. The group consisted of CGRP, blastic phase, acute posttranslational remission and secondary chronic phase with Ph ’positive acute lymph node. Six days or five days prior to bone marrow transplantation, high-dose cyclophosphamide 60 mg / kg / d was given 4 to 2 days prior to surgery, with a total of 10 Gy in 5 or a total of 12 Gy in 6 doses