乙型肝炎病毒(ＨＢＶ)感染对血液透析人群仍是一种常见的严重威胁。作者最近报告,对肌内接种未获免疫的患者随后每２周进行皮内接种可获得满意转化效果,但可惜免疫持续时间短得多。为了阐明此种短期免疫是否为皮内接种途径所固有,抑或由患者本身的独特状态(属对肌内接种无反应者)引起,作者在开始进 Hepatitis B virus (HBV) infection remains a common and serious threat to hemodialysis populations. The authors recently reported that satisfactory results were obtained for intramuscular inoculation of uninjured patients every 2 weeks followed by intradermal vaccination, but unfortunately the immunization duration was much shorter. In order to elucidate whether such short-term immunity is inherent in the intradermal route of inoculation or is caused by the patient’s own unique state of being non-responders to intramuscular injec- tion,