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目的探讨青年、老年初治涂阳肺结核全程间歇短程化疗效果。方法对63例60岁以上老年患者及69例青年初治涂阳患者进行疗效对比。结果规律治疗率:老年组:96.38%,青年组:98.55%。6个月疗程结束后青年组痰菌阴转率100%,老年组痰菌阴转率98.41%,两组之间差异无统计学意义(P>0.05)。结论笔者认为初治涂阳化疗方案2S3(E3)H3R3Z3/4H3R3,同样适合老年患者。按照中国结核病防治规划实施工作指南标准,确诊的初治涂阳患者,并严格执行全程监督管理,其痰菌转阴率、治疗率均能达到理想的效果。
Objective To investigate the effect of intermittent short-course chemotherapy for smear-positive pulmonary tuberculosis in young and old patients. Methods 63 cases of elderly patients over the age of 60 and 69 young patients with smear-positive patients were compared. The results of regular treatment rate: the elderly group: 96.38%, youth group: 98.55%. After six months of treatment, the sputum negative conversion rate was 100% in the youth group and the sputum negative conversion rate in the elderly group was 98.41%. There was no significant difference between the two groups (P> 0.05). Conclusion I believe that the initial treatment of smear chemotherapy 2S3 (E3) H3R3Z3 / 4H3R3, the same for elderly patients. In accordance with the guidelines for the implementation of guidelines for the implementation of TB prevention and control programs in China, newly diagnosed smear-positive patients were diagnosed and the whole supervision and management were strictly implemented. The negative conversion rate and the treatment rate of sputum bacteria could all achieve the desired results.