栓剂在我国古代国药剂型中已广为采用,如张仲景的伤寒论中载有蜜煎导方,便是一种治大便秘结的肛门栓剂;孙思邈的千金方中载有阴道栓剂的制法(将药末以绢袋盛大如指长三寸盛药满内妇人阴中……),葛洪的肘后方中有尿道栓剂的记载;王肯堂的澄治准绳中有塞鼻柱膏,也是一种用於鼻孔的栓剂。不但各种栓剂均有记载,且在制药技术上当时已知用熔点较低的羊脂作为栓剂基质。而在国外,也早在纪 Suppositories have been widely used in ancient China’s pharmacological types, such as Zhang Zhongjing’s typhoid fever theory, which contains a honey-fried derivative prescription, which is an anal suppository for the treatment of constipation. Sun Sini’s Qianjin Prescription contains a vaginal suppository preparation method ( In the case of a grandmother in a medicine bag with a three-inch-long pharmacy inside the woman’s yin ...), Ge Hong has a record of a urethral suppository at the back of the elbow; It is also a suppository for nostrils. Not only are all kinds of suppositories documented, but at the time it was known in the pharmaceutical art to use a lower melting suet as a suppository base. In foreign countries, it’s early