多囊卵巢综合征(polycystic ovarian syndrome,PCOS)是以持续性无排卵、高雄激素或胰岛素抵抗为特征的内分泌紊乱的症候群。研究认为PCOS可能始发于青春期并延续至成年,育龄期发病率为5%～10%,是一种遗传异质性、发病多因性,临床表现多样性的内分泌紊乱及代谢异常疾病。早在1935年,Stein和Leventhal首次描述该症,即双侧卵巢增大伴有闭经、月经稀发、多毛和肥胖,故该综合征又称为SteinLeventhal综合症。以后,Stein等发现对卵巢实施卵巢楔形切除 Polycystic ovarian syndrome (PCOS) is a syndrome of endocrine disorders characterized by persistent anovulation, hyperandrogenism, or insulin resistance. Studies suggest that PCOS may originate in adolescence and extend to adulthood, the incidence of childbearing age is 5% to 10%, is a genetic heterogeneity, multiple causes, clinical manifestations of endocrine disorders and metabolic disorders. As early as 1935, Stein and Leventhal first described the disorder as bilateral enlargement of the ovary accompanied by amenorrhea, oligomenorrhea, hirsutism and obesity, so the syndrome is also known as Stein Leventhal syndrome. Later, Stein and other found ovarian wedge resection